1 September, 2008
University of Manchester scientists have identified signalling activity between cells that are thought to determine the development of organs and tissues, as well as cancerous cells.
Members of The Faculty of Life Sciences at the University of Manchester have been studying the pathway that is known to be involved in the vast majority of pancreatic cancers and over half of all colorectal cancers.
Dr Hilary Ashe led a team of researchers in the project which could lead to the development of drugs which will interfere with this pathway, and therefore help treat these diseases.
Dr Ashe said: “This study has given us a new area to manipulate, making tumours more or less aggressive, by controlling how active this pathway is. In the future we could see compounds that are designed to make the regulation stronger, to work against a tumour or reverse kidney disease.”